Brand Story
24 Mar 2023, 10:13 GMT+10
As an expert in virology and microbiology, Creative Diagnostics recently introduced the Virus Yield Reduction Assay Service to support researchers in evaluating the antiviral activity of compounds, aiming to simplify the testing process and significantly reduce operations for customers.
Various techniques are currently utilized to assess the antiviral activity of compounds. Some popular procedures include plaque reduction, dye uptake, nucleic acid hybridization, and enzyme-linked immunosorbent assays. While the Virus Yield Reduction Assay is less common, which incubates a virus-infected culture with antiviral compounds for a period of time, allows the virus to replicate, and then titrates new native viruses with separate monolayer cultures.
Although the Virus Yield Reduction Assay allows quantitative measurement of infectious virus particle production in drug-treated cultures, the labor-intensive nature of this assay has so far prevented its widespread use as a routine technique. Creative Diagnostics now offers comprehensive services for Virus Yield Reduction Assay, and utilizes microtitration technology to streamline the testing process, significantly reducing the required operations.
Advantages of the Yield Reduction Assay:
Features
These assays are performed in three main steps, i.e., infection of cells in the presence of different concentrations of the test substance; collection of cells or cell culture supernatants at the end of the viral replication cycle; and determination of viral titers by plaque analysis, TCID50 or quantitative real-time PCR.
As an expert in the antiviral field, Creative Diagnostics offers a wide range of antiviral services to evaluate the inhibitory activity of candidate inhibitors. The company also provides a variety of tailored antiviral assays to reveal the action mechanism of new antiviral drugs. Creative Diagnostics has been developing and optimizing new antiviral assays for viruses, such as Dengue virus, Herpes simplex virus, Human cytomegalovirus (HCMV), Human influenza A virus, and Sindbis virus (SINV). Meanwhile, all antiviral studies can be performed in cytotoxicity assays in transformed or primary cells.
If you have questions regarding the Virus Yield Reduction Assay Service or other in vitro antiviral testing, please visit Creative Diagnostics at https://antiviral.creative-diagnostics.com.
About Creative Diagnostics
Headquartered in New York, Creative Diagnostics is a consulting and experimental service provider specializing in virology and microbiology. The company provides comprehensive solutions to conquer obstacles in virology and microbiology research, from high-security infrastructure provision, biosafety regulation elucidation, to expert viral system assistance.
Get a daily dose of The US News news through our daily email, its complimentary and keeps you fully up to date with world and business news as well.
Publish news of your business, community or sports group, personnel appointments, major event and more by submitting a news release to The US News.
More InformationWASHINGTON, D.C.: A federal rule designed to make it easier for Americans to cancel subscriptions has been blocked by a U.S. appeals...
BASTROP, Texas: In a surprising turn at Elon Musk's X platform, CEO Linda Yaccarino announced she is stepping down, just months after...
NEW YORK CITY, New York: Former British prime minister Rishi Sunak will return to Goldman Sachs in an advisory role, the Wall Street...
LONDON, U.K.: Physically backed gold exchange-traded funds recorded their most significant semi-annual inflow since the first half...
AMSTERDAM, Netherlands: Some 32 percent of global semiconductor production could face climate change-related copper supply disruptions...
NEW YORK, New York - U.S. stocks rebounded Tuesday with all the major indices gaining ground. Markets in the UK, Europe and Canada...
WASHINGTON, D.C.: A federal rule designed to make it easier for Americans to cancel subscriptions has been blocked by a U.S. appeals...
BASTROP, Texas: In a surprising turn at Elon Musk's X platform, CEO Linda Yaccarino announced she is stepping down, just months after...
NEW YORK CITY, New York: Former British prime minister Rishi Sunak will return to Goldman Sachs in an advisory role, the Wall Street...
LONDON, U.K.: Physically backed gold exchange-traded funds recorded their most significant semi-annual inflow since the first half...
AMSTERDAM, Netherlands: Some 32 percent of global semiconductor production could face climate change-related copper supply disruptions...
NEW YORK, New York - U.S. stocks rebounded Tuesday with all the major indices gaining ground. Markets in the UK, Europe and Canada...